Sour Grapefruit fans have said they’ve enjoyed its sativa and indica effects as a hybrid, which sometimes affect both the mind and the body. Reviewers have stated it may create a light euphoria that calms moods while focusing attention. Others have explained that they’ve used Sour Grapefruit to enhance their energy. Sour Grapefruit has also gained fans that enjoy conversation, as they’ve stated it can enhance social interactions.